Which source of supply is responsible for cradle-to-grave management of every AF weapon system?

The Air Force Materiel Command (AFMC) is responsible for cradle-to-grave management of every Air Force weapon system. This encompasses all phases of a weapon system's lifecycle, including research and development, acquisition, testing, and logistics support, as well as maintenance and disposal. AFMC ensures that each weapon system is effectively managed throughout its entire life, addressing the needs from design to retirement.

AFMC plays a critical role in integrating various logistics functions and provides the necessary resources, technical expertise, and management capabilities to oversee and sustain air systems. This comprehensive view of weapons system management includes not just initial procurement but also the ongoing support required to keep systems operational and effective in serving their intended roles in defense.

Other options, such as the Air Force Logistics Command, focused on different aspects of logistics and supply chain management but did not encompass the total lifecycle management. The Defense Logistics Agency, while significant in providing logistics and supply support for the Department of Defense, does not hold the same depth of responsibility specifically relating to Air Force weapon systems as AFMC. Local Manufacture refers to the production aspect, rather than overall management of weapon systems.